GeLC-MRM Quantitation of Mutant KRAS Oncoprotein in Complex Biological Samples
نویسندگان
چکیده
منابع مشابه
Quantitation of spatially-localized proteins in tissue samples using MALDI-MRM imaging.
MALDI imaging allows the creation of a "molecular image" of a tissue slice. This image is reconstructed from the ion abundances in spectra obtained while rastering the laser over the tissue. These images can then be correlated with tissue histology to detect potential biomarkers of, for example, aberrant cell types. MALDI, however, is known to have problems with ion suppression, making it diffi...
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ژورنال
عنوان ژورنال: Journal of Proteome Research
سال: 2012
ISSN: 1535-3893,1535-3907
DOI: 10.1021/pr300161j